Werner Poewe Selected Research

Restless Legs Syndrome (Restless Legs)

12/2019	Multimodal Magnetic Resonance Imaging reveals alterations of sensorimotor circuits in restless legs syndrome.
1/2018	Reflection impulsivity perceptual decision-making in patients with restless legs syndrome.
1/2016	Augmentation and impulsive behaviors in restless legs syndrome: Coexistence or association?
5/2012	Drug safety evaluation of rotigotine.
8/2011	Long-term safety and efficacy of rotigotine transdermal patch for moderate-to-severe idiopathic restless legs syndrome: a 5-year open-label extension study.
4/2011	Efficacy and augmentation during 6 months of double-blind pramipexole for restless legs syndrome.
10/2010	Rotigotine transdermal patch in moderate to severe idiopathic restless legs syndrome: a randomized, placebo-controlled polysomnographic study.
9/2010	Treatment of moderate to severe restless legs syndrome: 2-year safety and efficacy of rotigotine transdermal patch.
6/2009	The severity range of restless legs syndrome (RLS) and augmentation in a prospective patient cohort: association with ferritin levels.
3/2009	More on the restless legs syndrome and spinal anesthesia.

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Werner Poewe Research Topics

Disease

161	Parkinson Disease (Parkinson's Disease) 05/2024 - 03/2003
50	Multiple System Atrophy 12/2023 - 08/2003
38	Dyskinesias (Dyskinesia) 03/2024 - 01/2004
32	Parkinsonian Disorders (Parkinsonism) 12/2023 - 10/2003
20	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 08/2003
16	Disease Progression 11/2023 - 10/2003
15	Synucleinopathies 05/2023 - 09/2007
15	Dementia (Dementias) 01/2021 - 09/2003
14	Restless Legs Syndrome (Restless Legs) 12/2019 - 08/2005
12	Dystonia (Limb Dystonia) 01/2022 - 11/2006
11	Orthostatic Hypotension (Postural Hypotension) 09/2023 - 10/2011
10	Tremor (Tremors) 01/2023 - 08/2004
8	Psychotic Disorders (Schizoaffective Disorder) 01/2022 - 09/2003
7	Striatonigral Degeneration 12/2023 - 08/2003
7	Torticollis (Wryneck) 01/2019 - 01/2002
7	Friedreich Ataxia (Friedreich's Ataxia) 08/2013 - 11/2007
7	Disorders of Excessive Somnolence (Hypersomnia) 05/2012 - 03/2003
6	Cerebellar Ataxia (Dysmetria) 01/2022 - 03/2005
6	Movement Disorders (Movement Disorder) 12/2021 - 06/2006
6	Constipation 01/2021 - 11/2010
6	Nausea 08/2013 - 12/2004
5	Pain (Aches) 03/2024 - 10/2006
5	Hypokinesia (Bradykinesia) 01/2021 - 06/2006
5	REM Sleep Behavior Disorder 01/2020 - 02/2015
5	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2019 - 10/2011
5	Disruptive, Impulse Control, and Conduct Disorders (Kleptomania) 01/2018 - 05/2011
5	Fatigue 11/2013 - 05/2010
5	Sleepiness 07/2013 - 08/2006
5	Atherosclerosis 09/2009 - 09/2002
4	Olivopontocerebellar Atrophies (Olivopontocerebellar Atrophy) 12/2023 - 03/2005
4	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 01/2022 - 08/2006
4	Hallucinations (Hallucination) 11/2013 - 08/2008
3	Neuroinflammatory Diseases 01/2022 - 11/2007
3	Huntington Disease (Huntington's Disease) 12/2021 - 02/2005
3	Dystonic Disorders (Writer's Cramp) 01/2021 - 12/2005
3	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 12/2004
3	Cognitive Dysfunction 11/2015 - 09/2007
3	Dizziness (Lightheadedness) 02/2015 - 01/2011
3	Gliosis 03/2013 - 09/2009
3	Ataxia (Dyssynergia) 12/2011 - 06/2008
3	Autonomic Nervous System Diseases (Dysautonomia) 11/2010 - 03/2005
2	Injection Site Reaction 03/2024 - 11/2021
2	Body Weight (Weight, Body) 12/2022 - 07/2013
2	Tardive Dyskinesia 12/2021 - 11/2018
2	Drug-Induced Dyskinesia (Dyskinesia, Drug Induced) 01/2020 - 01/2015

Drug/Important Bio-Agent (IBA)

80	Levodopa (L Dopa)FDA LinkGeneric 03/2024 - 01/2004
30	SynucleinsIBA 02/2024 - 09/2007
17	Carbidopa (Lodosyn)FDA LinkGeneric 03/2024 - 07/2010
17	Biomarkers (Surrogate Marker)IBA 11/2023 - 10/2003
16	Pramipexole (Mirapex)FDA LinkGeneric 01/2022 - 08/2006
14	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 01/2020 - 10/2003
12	Dopamine Agonists (Dopamine Agonist)IBA 01/2023 - 09/2003
12	rasagiline (Azilect)FDA Link 01/2022 - 05/2005
12	alpha-SynucleinIBA 01/2021 - 08/2003
10	opicaponeIBA 11/2022 - 01/2016
10	Dopamine (Intropin)FDA LinkGeneric 01/2020 - 02/2005
9	Amantadine (Aman)FDA LinkGeneric 01/2023 - 08/2008
9	rotigotine FDA Link 03/2016 - 07/2008
8	entacapone (Comtan)FDA Link 11/2023 - 01/2004
8	Apomorphine FDA Link 01/2023 - 09/2015
8	IronIBA 12/2022 - 08/2005
8	Erythropoietin FDA Link 08/2013 - 11/2007
7	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 11/2023 - 06/2004
7	Rivastigmine (Exelon)FDA LinkGeneric 01/2014 - 12/2004
6	nabilone (Cesamet)FDA Link 03/2024 - 10/2006
6	Proteins (Proteins, Gene)FDA Link 05/2023 - 08/2003
6	Monoamine Oxidase (MAO)IBA 01/2023 - 04/2008
6	FrataxinIBA 08/2013 - 10/2008
5	salicylhydroxamic acid (SHAM)IBA 11/2018 - 11/2006
5	ropinirole (Requip)FDA LinkGeneric 08/2012 - 08/2006
4	serum P-component (CIt)IBA 05/2017 - 04/2011
4	Antidepressive Agents (Antidepressants)IBA 09/2015 - 02/2010
4	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2013 - 08/2011
4	3-nitropropionic acidIBA 05/2012 - 08/2003
4	Pergolide (Permax)FDA Link 10/2011 - 08/2006
3	Dronabinol (THC)FDA LinkGeneric 03/2024 - 10/2020
3	Clozapine (Clozaril)FDA LinkGeneric 01/2023 - 10/2011
3	CannabinoidsIBA 05/2022 - 10/2006
3	hydroxide ionIBA 01/2020 - 03/2012
3	AntibodiesIBA 01/2018 - 08/2015
3	Botulinum Toxins (Botulinum Toxin)IBA 09/2014 - 12/2005
3	Selegiline (E250)FDA LinkGeneric 08/2012 - 05/2005
3	Cabergoline FDA LinkGeneric 10/2011 - 08/2006
3	Type A Botulinum Toxins (Botox)FDA Link 10/2011 - 01/2002
3	Cholinesterase Inhibitors (Anticholinesterases)IBA 02/2009 - 09/2003
2	Antihypertensive Agents (Antihypertensives)IBA 04/2024 - 04/2016
2	SolutionsIBA 03/2024 - 11/2016
2	Monoclonal AntibodiesIBA 01/2022 - 01/2022
2	4-amino-4'-hydroxylaminodiphenylsulfone (HADS)IBA 01/2020 - 06/2007
2	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 01/2019 - 04/2016

Therapy/Procedure

62	Therapeutics 03/2024 - 01/2002
18	Deep Brain Stimulation 05/2024 - 06/2006
15	Activities of Daily Living (ADL) 11/2023 - 12/2004
5	Drug Therapy (Chemotherapy) 02/2024 - 03/2003
4	Transdermal Patch 03/2016 - 09/2010
3	Institutionalization (Institutionalized Persons) 01/2022 - 01/2019
3	Immunotherapy 01/2021 - 01/2018
3	Injections 09/2014 - 08/2004
3	Transplantation 09/2009 - 12/2005
2	Subcutaneous Infusions 03/2024 - 01/2018